Composite
Part:BBa_K1042015:Design
Designed by: Parth Patel Group: iGEM13_Gaston_Day_School (2013-09-26)
Cadmium Responsive GFP+Ogr Activator
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12INCOMPATIBLE WITH RFC[12]Illegal NheI site found at 200
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000INCOMPATIBLE WITH RFC[1000]Illegal BsaI.rc site found at 1200
Design Notes
After creating two intermediate parts, the upstream one being the Cadmium Promoter with Ogr Activator (BBa_K1042012) and the downstream one being the PO Promoter with GFP (BBa_K1042013), we digested the intermediates and ligated them to the linearized pSB1C3 plasmid provided. The resulting colonies were tested for responsive GFP production from the addition of cadmium.
Source
Intermediates:
Original Parts:
- Cadmium Promoter (BBa_K174015) registered by the Newcastle 2009 iGEM Team
- Ogr Activator from P2 Phage (BBa_I746350) registered by the Cambridge 2007 iGEM Team
- PO Promoter from P2 Phage (BBa_I746361) registered by the Cambridge 2007 iGEM Team
- GFP with stops (BBa_I13401) registered by the MIT 2005 iGEM Team